KMID : 0382320060260040113
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Environmental Mutagens and Carcinogens 2006 Volume.26 No. 4 p.113 ~ p.115
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Cytotoxcity Effects of Triphlorethol-A on Various Cancer Cells
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Kang Kyung-Ah
Hyun Jin-Won Lee Nam-Ho Piao Mei Jing Park So-Yoon Zhang Rui
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Abstract
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Ecklonia cava is a brown alga (Laminariaceae) that is abundant in the subtidal regions of Jeju island in Korea. Phlorotannins were identified to be responsible for the biological activities in Ecklonia species. In the present study, triphlorethol-A, a phlorotannin, was isolated from Ecklonia cava and its anticancer properties were investigated. Triphlorethol-A was investigated whether it may show cytotoxicity effects against U937, HeLa, NCI-H460 and MCF-7 cancer cells by MTT test. As a result, triphlorethol-A did not show cytotoxic effects against tested four cell lines.
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KEYWORD
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Triphlorethol-A, Ecklonia cava, Anticancer effect
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